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Research
1. Study on pathogenicity of the Aspergillus species in
experimentally immunosuppressed mice -
D. Chhabra and N. K. Dhakad
Vet World. 2008; 1(3): 69-70
Abstract
Aspergillus, a
saprophytic mould, distributed widely in the environment is a
frequently recognized etiological agent in a number of disease
conditions especially in immunocompromised patients. Mice
untreated as well as immunocompromised by administering
cortisone, were inoculated intraperitoneally with spores of Aspergillus spp.
The administration of cortisone rendered mice highly susceptible
to fatal visceral aspergillosis. Heat killed spores produced no
evident lesions in control or experimental mice.
Key words : Aspergillus,
Immunosuppression, Corticosteroid, mice.