Open Access
Review (Published online: 11-01-2022)
4. Zebrafish as an experimental model for the simulation of neurological and craniofacial disorders
Ashwin Rohan Rai, Teresa Joy, K. S. Rashmi, Rajalakshmi Rai, N. A. Vinodini and P. J. Jiji
Veterinary World, 15(1): 22-29

Ashwin Rohan Rai: Department of Anatomy, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Teresa Joy: Department of Anatomy, American University of Antigua College of Medicine, University Park, Coolidge, St. John's, Antigua.
K. S. Rashmi: Department of Physiology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Rajalakshmi Rai: Department of Anatomy, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
N. A. Vinodini: Department of Physiology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
P. J. Jiji: Department of Anatomy, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.

doi: www.doi.org/10.14202/vetworld.2022.22-29

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Article history: Received: 02-08-2021, Accepted: 30-11-2021, Published online: 11-01-2022

Corresponding author: Teresa Joy

E-mail: tjoy@auamed.net

Citation: Rai AR, Joy T, Rashmi KS, Rai R, Vinodini NA, Jiji PJ (2022) Zebrafish as an Experimental Model for the Simulation of Neurological and Craniofacial Disorders, Veterinary World, 15(1): 22-29.
Abstract

Zebrafish have gained momentum as a leading experimental model in recent years. At present, the zebrafish vertebrate model is increasingly used due to its multifactorial similarities to humans that include genetic, organ, and cellular factors. With the emergence of novel research techniques that are very expensive, it is necessary to develop affordable and valid experimental models. This review aimed to highlight some of the most important similarities between zebrafish and humans by emphasizing the relevance of the first in simulating neurological disorders and craniofacial deformity.

Keywords: craniofacial deformity, experimental model, neurological disorders, zebrafish.