Open Access
Copyright: The authors. This article is an open access
article licensed under the terms of the Creative Commons Attribution License
(http://creativecommons.org/licenses/by/2.0) which permits unrestricted use,
distribution and reproduction in any medium, provided the work is properly
cited.
Research
2.
Study of antipyretic activity of Bauhinia racemosa lam in
rats -
V. I. Borikar, C. R. Jangde, Preety Philip, D.S. Rekhe and S. K.
Atole
Vet World. 2009; 2(6): 215-216
Abstract
The study
was conducted to screen the antipyretic activity of alcoholic
extract of the stem bark of Bauhinia racemosa Lam. as per
the method described by Bhalla et.al. Thirty six
healthy rats weighing between 200-250gms were divided into six
groups of six animals each, with 50% sex ratio. The initial
rectal temperature of each animal was recorded by digital
thermometer and its hourly variation was noted for 3 hours. The
pyrexia was induced by injecting a suspension of 15% of brewer’s
yeast and 2% gum acacia in normal saline sub-cutaneously below
the nape of neck @ 1ml/100gm of animal weight. The difference in
temperature between 0 hour and respective time interval was
found out by statistical method. The potency of extract to bring
down the temperature was compared with that of the control
group. The extract showed marked antipyretic activity in a
dose dependent manner.
Keywords:
Bauhinia
racemosa,
brewer’s
yeast, gum acacia
