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Open Access
Copyright: The authors. This article is an open access
article licensed under the terms of the Creative Commons Attribution License
(http://creativecommons.org/licenses/by/2.0) which permits unrestricted use,
distribution and reproduction in any medium, provided the work is properly
cited.
Research
4.
Current trend of drug sensitivity in bovine mastitis -
Rajeev Ranjan, M. K. Gupta, Satparkash Singh and Sanjeev Kumar
Vet World. 2010; 3(1): 17-20
Abstract
The study
was conducted on 190 milk samples of bovine mastitis and 138
samples were confirmed positives for microorganisms. All the 138
samples were subjected to drug sensitivity test. The most
effective antibiotic was enrofloxacin (91.67%)
followed by ciprofloxacin (90.15%), amikacin (87.12%),
ceftriaxone
(84.10%),
chloramphenicol (80.31%), cefotaxime (79.55%)
and gentamicin (77.27%).
Microorganisms were mostly resistant to drugs like streptomycin, penicillinG, ampicillin, cloxacillin, amoxycillin and
neomycin in increasing order of resistance. Hence, it is
suggested that the line of treatment should be based on antibiogram study
of various isolates from bovine mastitis. Further, the selection
of drugs after culture and sensitivity test should be based on
their ability to cross blood tissue barrier or mammary
parenchyma, lipophilicity and
ability to work in alkaline pH.
Key words:
bovine mastitis, drug sensitivity, microorganism, pH, lipid
solubility.
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