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Review
13.
Ovarian stem cells and neo-oogenesis: A breakthrough
in reproductive biology research -
S. Mooyottu, S. Anees, S. Cherian
Vet World. 2011; 4(2): 89-91
doi:
10.5455/vetworld.2011.89-91
Abstract
The concept of ovarian stem cells which can
replenish the ovarian reserve in postnatal mammalian
females is a revolutionary breakthrough in
reproductive biology. This idea overturned the
central dogma existed in female reproductive
physiology. Contradicting the popular belief that
oogenesis does not occur in post natal life,
researchers proved the existence of putative stem
cells in ovary, which can supply functional
follicles in post natal ovaries. Even though the
idea of neo-oogenesis in postnatal ovaries in normal
conditions is controversial, the isolation and
manipulation of ovarian stem cells have got
tremendous application in medical, veterinary and
animal production fields.
Key words: Germline
stem cells (GSC), Ovarian stem cells, Neo-oogenesis