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Research
(Published
online: 18-10-2014)
16.
Electrocardiographic and hemato-biochemical effects of two
balanced anesthetic protocols in dogs - Anubhav Khurana,
Adarsh Kumar, Sandeep Kumar Sharma and Amit Kumar
Veterinary World, 7(10): 835-841
doi:
10.14202/vetworld.2014.835-841
Anubhav
Khurana:
Department of Veterinary Surgery and Radiology, Dr. G.C. Negi
College of Veterinary and Animal Sciences, CSKHPKV, Palampur,
Himachal Pradesh, India;
anubhav.khurana@gmail.com
Adarsh
Kumar: Department
of Veterinary Surgery and Radiology, Dr. G.C. Negi College of
Veterinary and Animal Sciences, CSKHPKV, Palampur, Himachal
Pradesh, India;
adarsh9kan@gmail.com
Sandeep
Kumar Sharma:
Department of Veterinary Surgery and Radiology, Dr. G.C. Negi
College of Veterinary and Animal Sciences,
CSKHPKV,
Palampur, Himachal Pradesh, India;
sandeepsharma956@gmail.com
Amit
Kumar: Department of Veterinary Surgery and Radiology, Dr. G.C.
Negi College of Veterinary and Animal Sciences, CSKHPKV, Palampur,
Himachal Pradesh, India;
drasingla@gmail.com
Received:
30-06-2014, Revised: 08-09-2014, Accepted: 13-09-2014, Published
online: 18-10-2014
Corresponding author:
Anubhav Khurana, e-mail: anubhav.khurana@gmail.com
Abstract
Aim:
The purpose of this study was to compare the
electrocardiographic (ECG), hematological and clinico-biochemical
effects of two balanced anesthetic protocols in dogs.
Materials and Methods: A total of 20 clinical cases of dogs,
randomly divided into two groups of 10 animals each were made part
of study. All dogs were premedicated with injection atropine
sulfate @ 0.04 mg/kg body weight (b. wt.) subcutaneously followed
15 min later with injection butorphanol tartarate @ 0.2 mg/kg b.
wt. intravenous (IV). Subsequently after 10 min premedicated with
injection diazepam @ 0.5 mg/kg b. wt. IV (Group DP) or injection
acepromazine maleate @ 0.015 mg/kg b. wt. IV (Group AP) followed
by injection propofol “till effect” IV for induction of surgical
anesthesia. The animals were immediately transferred to halothane
in oxygen. Observations recorded in dogs included ECG recordings,
hematological and clinico-biochemical observations at various time
intervals.
Results: No arrhythmia was observed in any animal
pre-operatively and intra-operatively in any of the groups.
Significant fall in packed cell volume (PCV) and total erythrocyte
count occurred in DP group in early phase, whereas only PCV
decreased significantly in AP group. Biochemical parameters were
non-significant in both the groups.
Conclusion: Both diazepam-butorphanol-propofol-halothane and
acepromazine-butorphanol-propofol-halothane are safe with respect
to their ECG, hematological and biochemical effects in clinical
cases.
Keywords: acepromazine, butorphanol, diazepam, dog, propofol.
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