Veterinary World

     Open access and peer reviewed journal  

ISSN (Online): 2231-0916

 

Home l Editorial board l Instructions for authors l Reviewer guideline l Open access policy l Archives l FAQ


Open Access

Copyright: The authors. This article is an open access article licensed under the terms of the Creative Commons Attribution License

(http://creativecommons.org/licenses/by/2.0) which permits unrestricted use, distribution and reproduction in any medium, provided the work is properly cited.


Research (Published online: 19-09-2015)

10. Incidence and clinical vital parameters in primary ketosis of Murrah buffaloes - Ankit Kumar, Neelesh Sindhu, Parmod Kumar, Tarun Kumar, Gaurav Charaya, Surbhi, V. K. Jain and Sridhar

Veterinary World, 8(9): 1083-1087

 

 

   doi: 10.14202/vetworld.2015.1083-1087

 

Ankit Kumar: Department of Veterinary Medicine, Lala Lajpat Rai University of Veterinary & Animal Sciences, Hisar - 125 004, Haryana, India; ankitk813@gmail.com

Neelesh Sindhu: Teaching Veterinary Clinical Complex, Lala Lajpat Rai University of Veterinary & Animal Sciences, Hisar - 125 004, Haryana, India; drneeleshsindhu@gmail.com

Parmod Kumar: Department of Veterinary Medicine, Lala Lajpat Rai University of Veterinary & Animal Sciences, Hisar - 125 004, Haryana, India; pdhuran09@gmail.com

Tarun Kumar: Teaching Veterinary Clinical Complex, Lala Lajpat Rai University of Veterinary & Animal Sciences, Hisar - 125 004, Haryana, India; tarunvet@gmail.com

Gaurav Charaya: Department of Veterinary Medicine, Lala Lajpat Rai University of Veterinary & Animal Sciences, Hisar - 125 004, Haryana, India; gcharaya9@gmail.com

Surbhi: Department of Veterinary Physiology and Biochemistry, Lala Lajpat Rai University of Veterinary & Animal Sciences, Hisar - 125 004, Haryana, India; surbhi804@gmail.com

V. K. Jain: Department of Veterinary Medicine, Lala Lajpat Rai University of Veterinary & Animal Sciences, Hisar - 125 004, Haryana, India; vkjainluvas@gmail.com

Sridhar: Department of Veterinary Medicine, Lala Lajpat Rai University of Veterinary & Animal Sciences, Hisar - 125 004, Haryana, India; drsrishar_saxena@gmail.com

 

Received: 23-05-2015, Revised: 12-08-2015, Accepted: 17-08-2015, Published online: 19-09-2015

 

Corresponding author: Neelesh Sindhu, e-mail: drneeleshsindhu@gmail.com


Citation: Kumar A, Sindhu N, Kumar P, Kumar T, Charaya G, Surbhi, Jain VK, Sridhar (2015) Incidence and clinical vital parameters in primary ketosis of Murrah buffaloes, Veterinary World 8(9): 1083-1087.



Aim: The present study was undertaken to ascertain the incidence and clinical vital parameters in cases of primary ketosis in Murrah buffaloes brought to teaching veterinary clinical complex, Lala Lajpat Rai University of Veterinary and Animal Sciences, Hisar and from adjoining villages of the district Hisar, Haryana, India.

Materials and Methods: The investigation was conducted on 24 clinical cases (out of total 145 screened) of primary ketosis. The diagnosis was confirmed on the basis of clinical signs and significantly positive two tests for ketone bodies in urine (Rothera’s and Keto-Diastix strip test). Data collected were statistically analyzed using independent Student’s t-test.

Results: Overall incidence of disease in these areas was found to be 16.55% and all the animals were recently parturited (mean: 1.42±0.14 month), on an average in their third lactation (mean: 2.38±0.30) and exhibited clinical signs such as selective anorexia (refusal to feed on concentrate diet), drastic reduction in milk yield (mean: 64.4±5.35%), ketotic odor from urine, breath, and milk and rapid loss of body condition. All the clinical vital parameters in ketotic buffaloes (body temperature, heart rate, respiration rate, and rumen movements) were within normal range.

Conclusion: Primary ketosis in Murrah buffaloes was the most common seen in the third lactation, within the first 2 months after parturition with characteristics clinical signs and no variability in vital parameters. The disease has severe effect on the production status of affected animal.

Keywords: buffaloes, incidence, Keto-Diastix strip test, primary ketosis, Rothera’s test.



1. Zhang, Z., Liu, G., Wang, H., Li, X. and Wang, Z. (2012) Detection of subclinical ketosis in dairy cows. Pak. Vet. J., 32(2): 156-160.
 
2. Radostits, O.M., Blood, D.C. and Gay, C.C. (1994) Veterinary Medicine. 8th ed. ELBS, Baillier Tindall, London.
PMid:8076288 PMCid:PMC1686246
 
3. Sarode, D.B., Nisal, M.B. and Sapre, V.A. (1981) Note on bovine ketosis. Indian J. Anim. Sci., 51: 228.
 
4. Bauman, D.E. and Currie, W.B. (1980) Partitioning of nutrients during pregnancy and lactation: A review of mechanisms involving homeostasis and homeorhesis. J. Dairy Sci., 63(9): 1514-1529.
http://dx.doi.org/10.3168/jds.S0022-0302(80)83111-0
 
5. Butler, W.R. and Smith, R.D. (1989) Interrelationships between energy balance and postpartum reproductive function in dairy cattle. J. Dairy Sci., 72(3): 767-783.
http://dx.doi.org/10.3168/jds.S0022-0302(89)79169-4
 
6. Collard, B.L., Boettcher, P.J., Dekkers, J.C.M., Petitclerc, D. and Schaeffer, L.R. (2000) Relationships between energy balance and health traits of dairy cattle in early lactation. J. Dairy Sci., 83(11): 2683-2690.
http://dx.doi.org/10.3168/jds.S0022-0302(00)75162-9
 
7. Duffield, T.F., Lissemore, K.D., McBride, B.W. and Leslie, K.E. (2009) Impact of hyperketonemia in early lactation dairy cows on health and production. J. Dairy Sci., 92(2): 571-580.
http://dx.doi.org/10.3168/jds.2008-1507
PMid:19164667
 
8. LeBlanc, S.J., Leslie, K. and Duffield, T.F. (2005) Metabolic predictors of displaced abomasum in dairy cattle. J. Dairy Sci., 88(1): 159-170.
http://dx.doi.org/10.3168/jds.S0022-0302(05)72674-6
 
9. McArt, J.A., Nydam, D.V. and Oetzel, G.R. (2012b) Epidemiology of subclinical ketosis in early lactation dairy cattle. J. Dairy Sci., 95: 5056-5066.
http://dx.doi.org/10.3168/jds.2012-5443
PMid:22916909
 
10. Busato, A., Faissler, D., Küpfer, U. and Blum, J.W. (2002) Body condition scores in dairy cows: Associations with metabolic and endocrine changes in healthy dairy cows. J. Vet. Med. Ser. A., 49: 455-460.
http://dx.doi.org/10.1046/j.1439-0442.2002.00476.x
 
11. Gillund, P., Reksen, O., Grohn, Y.T. and Karlberg, K. (2001) Body condition related to ketosis and reproductive performance in Norwegian dairy cows. J. Dairy Sci., 84(6): 1390-1396.
http://dx.doi.org/10.3168/jds.S0022-0302(01)70170-1
 
12. McArt, J.A., Nydam, D.V. and Oetzel, G.R. (2013) Dry period and parturient predictors of early lactation hyperketonemia in dairy cattle. J. Dairy Sci., 96(1): 198-209.
http://dx.doi.org/10.3168/jds.2012-5681
PMid:23102961
 
13. Rastani, R.R., Grummer, R.R., Bertics, S.J., Gümen, A., Wiltbank, M.C., Mashek, D.G. and Schwab, M.C. (2005) Reducing dry period length to simplify feeding transition cows: Milk production, energy balance, and metabolic profiles. J. Dairy Sci., 88(3): 1004-1014.
http://dx.doi.org/10.3168/jds.S0022-0302(05)72768-5
 
14. Santschi, D.E., Lefebvre, D.M., Cue, R.I., Girard, C.L. and Pellerin. D. (2011) Incidence of metabolic disorders and reproductive performance following a short (35-d) or conventional (60-d) dry period management in commercial Holstein herds. J. Dairy Sci., 94(7): 3322-3330.
http://dx.doi.org/10.3168/jds.2010-3595
PMid:21700018
 
15. Watters, R.D., Guenther, J.N., Brickner, A.E., Rastani, R.R., Crump, P.M., Clark, P.W. and Grummer, R.R. (2008) Effects of dry period length on milk production and health of dairy cattle. J. Dairy Sci., 91(7): 2595-2603.
http://dx.doi.org/10.3168/jds.2007-0615
PMid:18565918
 
16. Duffield, T.F. (2000) Subclinical ketosis in lactating dairy cattle. Vet. Clin. North Am. Food Anim. Pract., 16(2): 231-253.
PMid:11022338
 
17. Grohn, Y., Erb, H.N., McCulloch, C.E. and Saloniemi, H.S. (1989) Epidemiology of metabolic disorders in dairy cattle; association among host characteristics, disease and production. J. Dairy Sci., 72(7): 1876-1885.
http://dx.doi.org/10.3168/jds.S0022-0302(89)79306-1
 
18. Singh, B. and Kasaralikar, V.R. (1988) Prevalence, biochemistry and treatment of clinical ketosis in buffalo (Bubalus bubalis). Abstr. 367-II. World Buffalo Congress, New Delhi; December, 12-17.
 
19. Rautmare, S.S., Anantwar, L.G. and Singh B. (1989) Prevalence of ketosis in buffalo (Bubalus bubalis). Indian J. Vet. Med., 9: 28.
 
20. Anantwar, L.G. and Singh, B. (1993) Epidemiology, clinicopathology and treatment of clinical ketosis in buffaloes (Bubalus bubalis). Indian Vet. J., 70: 152-156.
 
21. Asrat, M., Tadesse, G.H., Gounder, R.V. and Nagappan, R. (2013) Prevalence and treatment of ketosis in dairy cows in and around Addis Ababa, Ethiopia. Br. J. Dairy Sci., 3(3): 26-30.
 
22. Das, A., Sahoo, N., Samal, P.C., Ray, P.K., Karna, D.K. (2008) Incidence of perparturient diseases among jersey cows in an organized farm. Indian. Vet. J., 85(7): 716-718.
 
23. LeBlanc, S. (2010) Monitoring metabolic health of dairy cattle in the transition period. J. Reprod. Dev., 56: S29-S35.
http://dx.doi.org/10.1262/jrd.1056s29
 
24. Rasmussen, L.K., Nielsen, B.L., Pryce, J.E., Mottram, T.T. and Veerkamp, R.F. (1999) Risk factors associated with the incidence of ketosis in dairy cows. J. Anim. Sci., 68: 379-386.
 
25. Rautmare, S.S. and Anantwar, L.G. (1993) Prevalence, biochemistry and treatment of clinical ketosis in buffaloes. Buffalo Bull., 12(4): 81-83.
 
26. Stengärde, L., Holtenius, K., Emanuelson, U., Hultgren, J., Niskanen, R. and Tråvén, M. (2011) Blood parameters in Swedish dairy herds with high or low incidence of displaced abomasum or ketosis. Vet. J., 190(1): 124-130.
http://dx.doi.org/10.1016/j.tvjl.2010.09.011
PMid:21982532
 
27. Suthar, V.S., Canelas-Raposo, J., Deniz, A. and Heuwieser, W. (2013) Prevalence of subclinical ketosis and relationships with postpartum diseases in European dairy cows. J. Dairy Sci., 96(5): 2925-2938.
http://dx.doi.org/10.3168/jds.2012-6035
PMid:23497997
 
28. Vermunt, J. (1987) A brief review and observations on clinical ketosis in non-lactating dairy cattle. N. Z. Vet. J., 35: 121-123.
http://dx.doi.org/10.1080/00480169.1987.35408
PMid:16031401
 
29. Aiello, S. (2010) The Merck Veterinary Manual. 10th ed. Wiley, Philadelphia, Pennsylvania, USA. p933-935.
 
30. Chugh, S.K., Bhardwaj, R.M. and Malik, K.S. (1992) Nervous form of ketosis in a cow: A case report. Indian J. Vet. Med., 12: 60-61.
 
31. Farag, E.A. and Metwally, A.M. (2012) Markers used for prediction of ketosis and milk fever in dairy buffaloes at Kaliobeia governorate. Glob. Vet., 9: 1-7.
 
32. Mir, A.Q. and Malik, H.U. (2003) Utility of clinical symptomatology in diagnosis of bovine ketosis under field conditions. Abstract in: National Symposium and XXI ISVM Convention, Anand, Gujarat.
 
33. Mutlu, S. and Abdullah, B. (1998) The clinical-chemical parameters, serum lipoproteins and fatty infiltration of the liver in Ketotic Cows. Turk. J. Vet. Anim. Sci., 22: 443-447.
 
34. Reddy, B.S., Reddy, B.S.S., Reddy, Y.P. and Vennkatasivakumar, R. (2014) Nervous form of ketosis in cows and its treatment. Int. J. Biol. Res., 2(2): 143-144.
http://dx.doi.org/10.14419/ijbr.v2i2.3591
 
35. Sahinduran, S., Sezer, K., Buyukoglu, T., Albay, M.K. and Karakurum, M. C. (2010) Evaluation of some haematological and biochemical parameters before and after treatment in cows with ketosis and comparison of different treatment methods. J. Anim. Vet. Adv., 9: 266-271.
http://dx.doi.org/10.3923/javaa.2010.266.271
 
36. Tadesse, G., Bekelle, D. and Singh, B. (2012) Prevalence and clinico-pathology of ketosis in dairy cows in Tigray region of Ethiopia. Momona Ethiopian J. Sci., 4(1): 115-120.
 
37. Venkateshwarulu, K. and Rao, D.S.T. (1994) Clinical and biochemical findings in subclinical ketosis in cross bred cows. Indian. J. Vet. Med., 14: 6-8.