Vet World Vol.10 September-2017 Article-9
Research Article
Veterinary World, 10(9): 1063-1065
https://doi.org/10.14202/vetworld.2017.1063-1065
Detection of anti-Toxoplasma gondii antibodies in chronic myeloid leukemia and acute myeloid leukemia patients
2. Department of Parasitology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Background and Aim: Infection of Toxoplasma gondii is a worldwide distribution. Toxoplasmosis in patients who are immunocompromised by virtue of underlying leukemia disease has received relatively little attention. This study was aimed to evaluate IgG and IgM antibodies of T. gondii and to minimize the role of T. gondii and opportunistic infection complication at the early stage of infection in leukemia patients.
Materials and Methods: The purpose of this assay was to measure anti-T. gondii IgG and IgM antibodies by enzyme-linked immunosorbent assay (ELISA) technique in leukemia patients.
Results: IgG antibodies against T. gondii were detected by ELISA in 96 (56.4%) leukemia patients and 72 (42.4%) control group. IgM antibodies were found in 10 patients (5.9%) with leukemia and 3 (1.8%) in the corresponding.
Conclusion: Our finding indicated that leukemia patients under immunosuppressive condition should not be neglected. Toxoplasmosis in leukemia patients as a main risk factor is considered, meanwhile in some patients, due to possibility of the presence of secondary infection that leads to severe toxoplasmosis. Keywords: acute myeloid leukemia, chronic myeloid leukemia, Toxoplasma gondii.
Keywords: acute myeloid leukemia, chronic myeloid leukemia, Toxoplasma gondii.
How to cite this article: Gharavi MJ, Roozbehani M, Mandeh Z (2017) Detection of anti-Toxoplasma gondii antibodies in chronic myeloid leukemia and acute myeloid leukemia patients, Veterinary World, 10(9): 1063-1065.
Received: 21-04-2017 Accepted: 14-08-2017 Published online: 13-09-2017
Corresponding author: Mona Roozbehani E-mail: mona.roozbehani@yahoo.com
DOI: 10.14202/vetworld.2017.1063-1065
Copyright: Gharavi, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.