Determination of natural antibodies, beta-hydroxybutyric acid, and non-esterified fatty acid levels in the serum of peripartum Tuj and Hem&scedil;in sheep

Vet World Vol.14 April-2021 Article-27

Research Article

Veterinary World, 14(4): 1002-1006

https://doi.org/10.14202/vetworld.2021.1002-1006

Cihan Kaçar¹, Semra Kaya¹, Mushap Kuru¹, Ekin Emre Erkiliç², Metin Öğün³, Hasan Oral¹, and Murat Can Demir¹

1. Department of Obstetrics and Gynecology, Faculty of Veterinary Medicine, Kafkas University, 36100 Kars, Turkey.
2. Department of Internal Medicine, Faculty of Veterinary Medicine, Kafkas University, 36100 Kars, Turkey.
3. Department of Biochemistry, Faculty of Medicine, Kafkas University, 36100 Kars, Turkey.

Background and Aim: Many metabolic and immunological changes occur during the transition period. Innate immunity plays an important role against to infections and natural antibodies (NAb) are important in immunity. This study aims to determine a connection between serum NAb titers, beta-hydroxybutyric acid (BHBA), and non-esterified fatty acid (NEFA) concentrations in Tuj and Hemsin sheep during the peripartum period.

Materials and Methods: Serum NAb, BHBA, and NEFA levels were determined from the blood samples collected from Tuj and Hemsin sheep on days 30 and 15 before birth, on the day of birth (day 0), and on days 15 and 30 after birth.

Results: NAb titers were found to be higher in Tuj than in Hemsin sheep (p<0.001). No statistically significant difference was found in serum BHBA concentrations of both breeds on all sampling days (p>0.05). The serum NEFA level was lower in Tuj sheep in the last 15 days of pregnancy compared to Hemsin sheep (p<0.05), while no difference was found in samples collected at the other time points.

Conclusion: This study indicated that serum NAb titers significantly changed in Tuj and Hemsin sheep during the transition period. Serum BHBA and NEFA concentrations increased during the last stages of pregnancy and decreased after birth. Based on these findings, it is suggested that the immunological status could vary by the breed of sheep or various factors that affect the sheep's metabolic state. Keywords: beta-hydroxybutyric acid, ewe, natural antibody, non-esterified fatty acid, peripartum period.

Keywords: beta-hydroxybutyric acid, ewe, natural antibody, non-esterified fatty acid, peripartum period.

How to cite this article: Kaçar C, Kaya S, Kuru M, Erkiliç EE, Öğün M, Oral H, Demir MC (2021) Determination of natural antibodies, beta-hydroxybutyric acid, and non-esterified fatty acid levels in the serum of peripartum Tuj and Hemsin sheep, Veterinary World, 14(4): 1002-1006.

Received: 18-11-2020 Accepted: 04-03-2021 Published online: 26-04-2021

Corresponding author: Semra Kaya E-mail: semra-kafkas@hotmail.com

DOI: 10.14202/vetworld.2021.1002-1006

Copyright: Kaçar, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.