Dried bovine placenta improves spermatozoa count in a rat model of male reproductive aging

Vet World Vol.14 June-2021 Article-25

Research Article

Veterinary World, 14(6): 1602-1607

https://doi.org/10.14202/vetworld.2021.1602-1607

Surya Agus Prihatno¹, Yosua Kristian Adi¹, Teguh Budipitojo², Topas Wicaksono Priyo Jr¹, and Yonathan Alvin Maruli Asi Sihotang³

1. Department of Reproduction and Obstetric, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.
2. Department of Anatomy, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.
3. Sains Veteriner Magister, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta 55281, Indonesia.

Background and Aim: In the male reproductive system, the aging process can lead to infertility. Recently, placenta and its derivatives have been researched as regenerative agents. This study aimed to describe the basic components of dried bovine placenta powder and its potential effects as a regenerative agent in a rat model of male reproductive aging with D-galactose induction.

Materials and Methods: We divided 15 male Wistar rats, 2 months of age, into three groups: A, the health control group; B, the D-galactose induction group, and C, the D-galactose induction and 10% dried bovine placenta supplementation group. We measured epididymal sperm concentration and testicular weight and volume and analyzed these using one-way analysis of variance.

Results: Dried bovine placenta was rich in nutrients, with 61.98% protein, 21.25±2.07 carbohydrates, 8.58% water, 4.93% ash, and 3.27% fat. The mean epididymal spermatozoa concentration of the rats in Groups A, B, and C was 3026×106/mL, 1492.8×106/mL, and 2732.5×106/mL, respectively. The average total testicle weights were 2.44 g, 2.72 g, and 2.57 g, respectively. The average total testicle volumes were 2.29 cm3, 2.49 cm3, and 2.33cm3, respectively.

Conclusion: Dried bovine placenta powder is rich in nutrients, especially protein. Supplementation with dried bovine placenta can improve epididymal spermatozoa concentration that is important in fertility. Keywords: aging, bovine placenta, male reproductive, sperm count, testicular.

Keywords: aging, bovine placenta, male reproductive, sperm count, testicular.

How to cite this article: Prihatno SA, Adi YK, Budipitojo T, Priyo Jr TW, Sihotang YAMA (2021) Dried bovine placenta improves spermatozoa count in a rat model of male reproductive aging, Veterinary World, 14(6): 1602-1607.

Received: 11-01-2021 Accepted: 06-05-2021 Published online: 21-06-2021

Corresponding author: Surya Agus Prihatno E-mail: prihatno@ugm.ac.id

DOI: 10.14202/vetworld.2021.1602-1607

Copyright: Prihatno, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.