Fertility restoration of racing mare with persistent corpus luteum

Vet World Vol.14 September-2021 Article-9

Research Article

Veterinary World, 14(9): 2356-2361

https://doi.org/10.14202/vetworld.2021.2356-2361

Tjok Gde Oka Pemayun¹, Imam Mustofa², Laba Mahaputra^2,3, Herry Agoes Hermadi², Ngakan Made Rai Wijaya⁴, Sri Mulyati², Suzanita Utama², Tjuk Imam Restiadi², and Rimayanti Rimayanti²

1. Laboratory of Veterinary Reproduction, Faculty of Veterinary Medicine, Udayana University, Jl. PB Sudirman, Denpasar, Bali 80233 Indonesia.
2. Division of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga, Kampus C Mulyorejo, Surabaya 60115, Indonesia.
3. Head Section of Health and Husbandry of the Indonesian Equestrian Association, East Java Region, Kampus C Mulyorejo, Surabaya 60115, Indonesia.
4. Division of Basic Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Kampus C Mulyorejo, Surabaya 60115, Indonesia.

Background and Aim: Persistent corpus luteum (PCL) causes anestrus in mares. This study aimed to determine the effect of intrauterine prostaglandin F2α (PGF2α) treatment on PCL of racing mares to restore fertility.

Materials and Methods: Twelve racing mares suspected with PCL were diagnosed using transrectal palpation and confirmed by serum progesterone (P4) concentration measurement. PGF2α was infused intrauterine, followed by serum collection at 24, 48, and 72 h after. Estrous symptoms were monitored, and mating was conducted on day 3 of estrus with an earlier injection of 8.4 μg gonadotropin-releasing hormone twice a day. Transrectal palpation was performed on days 21-30 to observe the corpus luteum. Pregnancy diagnosis was performed rectally on 40-45 days post-mating and confirmed using Doppler ultrasound scanning.

Results: Eleven of the 12 mares had PCL. There was a dramatic reduction in the P4 concentration following PGF2α treatment of mares with PCL. All mares exhibited estrus 2.6±0.55 days post-treatment with a P4 concentration of 0.12±0.12 ng/mL. Rectal palpation and P4 concentration on 21-30 days after estrous onset showed that all mares were ovulating. The evaluation of P4 concentration on days 40-45 post-mating showed that all mares were still in the luteal phase. However, the pregnancy rate was only 54.5% based on rectal palpation and Doppler ultrasound scanning.

Conclusion: Treatment of PCL in racing mares with an intrauterine infusion of PGF2α restored the estrous cycle and induced ovulation and pregnancy. Keywords: estrus, fertility, good health and well-being, ovulation, progesterone, racing mare.

Keywords: estrus, fertility, good health and well-being, ovulation, progesterone, racing mare.

How to cite this article: Pemayun TGO, Mustofa I, Mahaputra L, Hermadi HA, Wijaya NMR, Mulyati S, Utama S, Restiadi TI, Rimayanti R (2021) Fertility restoration of racing mare with persistent corpus luteum, Veterinary World, 14(9): 2356-2361.

Received: 05-05-2021 Accepted: 02-08-2021 Published online: 08-09-2021

Corresponding author: Imam Mustofa E-mail: imam.mustofa@fkh.unair.ac.id

DOI: 10.14202/vetworld.2021.2356-2361

Copyright: Pemayun TGO, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.