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Research
1.
Peste des petits ruminants serological survey in
Karamoja sub region of Uganda by competitive ELISA -
Bonny Mulindwa, Simon Petter Ruhweza, Chrisostom
Ayebazibwe, Frank Norbert Mwiine, Dennis Muhanguzi,
OlahoMukani William
Vet World. 2011; 4(4): 149-152
doi:
10.5455/vetworld.2011.149-152
Abstract
Following the historical reports of mysterious
illnesses and deaths in goats in the Karamoja
sub-region in April, 2007 and subsequent
confirmation of Pest des Petitis Ruminants in
July, 2007; we carried out a serological survey to
determine the indicative caprine PPRV exposure
rate by 2009. We sampled 280 goats from Moroto,
Nakapiripirit, Abim and Kotido Districts of
North-eastern Uganda to detect antibodies against
PPRV using competitive enzyme linked immunosorbent
assay (cELISA). The prevalence of PPRV antibodies
in the districts of Moroto, Nakapiripirit, Kotido
and Abim was 63.2% (CI = 95%, 58.0 – 68.0%), 72.0%
(CI = 95%, 65.6 - 78.4%), 85% (CI = 95%, 81.0 –
88.9%) and 1.6% (CI = 95%, -0.01 – 3.22%)
respectively. The overall prevalence of antibodies
against PPRV in Karamoja sub-region was found to
be 57.6 % (CI = 95%, 48.8 – 66.4%). The high
prevalence of antibodies against PPRV suggests
that active infection may still be present and
therefore the need to institute disease control
measures. More studies should be undertaken to
characterize the viruses involved and the
epidemiology of PPR in Uganda.
Keywords:
Goats, Competitive (ELISA), Karamoja, Peste des
petits ruminants Virus (PPRV), PPRV antibodies.
