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              Open Access  
Copyright: The authors. This article is an open access 
article licensed under the terms of the Creative Commons Attribution License 
(http://creativecommons.org/licenses/by/2.0) which permits unrestricted use, 
distribution and reproduction in any medium, provided the work is properly 
cited. 
 
                              
                              
                              Review Article 
                              
                              10. 
                              
                              Vibrio parahaemolyticus- An emerging 
                              foodborne pathogen -
                              
                              
                              S Nelapati, K Nelapati and B K ChinnamVet World. 2012; 5(1): 48-63
 
                
              doi: 
              10.5455/vetworld.2012.48-62 
                
              
              
          
 
              Abstract 
 
                              
                              Vibrio parahaemolyticus is a halophilic gram 
                              negative, motile, oxidase positive, straight or 
                              curved rod-shaped, facultative anaerobic bacteria 
                              that occur naturally in the marine environment. 
                              They form part of the indigenous microflora of 
                              aquatic habitats of various salinity and are the 
                              major causative agents for some of the most 
                              serious diseases in fish, shellfish and penacid 
                              shrimp. This human pathogen causes acute 
                              gastroenteritis characterized by diarrhea, 
                              vomiting and abdominal cramps through consumption 
                              of contaminated raw fish or shellfish. V. 
                              parahaemolyticus is the leading cause of 
                              gastroenteritis due to the consumption of seafood 
                              worldwide. The incidence of V. parahaemolyticus 
                              infection has been increasing in many parts of the 
                              world, due to the emergence of O3:K6 serotype 
                              carrying the tdh gene which is responsible for 
                              most outbreaks worldwide. The pathogenicity of 
                              this organism is closely correlated with the 
                              Kanagawa phenomenon (KP +) due to production of 
                              Kanagawa hemolysin or the thermostable direct 
                              hemolysin (TDH). The TDH and TRH (TDH-related 
                              hemolysin) encoded by tdh and trh genes are 
                              considered to be important virulence factors. 
               
                              
              
                              Keywords: Vibrio parahaemolyticus, Kanagawa 
                              test, tdh, trh, sea foodborne pathogen, 
                              facultative anaerobic organism. 
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