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Review Article
12.
Genomic selection - Revolutionary breeding practice
in domestic animals -
Manjit Panigrahi, Subhashree Parida
Vet World. 2012; 5(7): 433-436
doi:
10.5455/vetworld.2012.4
33-436
Abstract
With more and
more Single Nucleotide Polymorphisms (SNPs) being
identified throughout the genome, some of those SNPs
will be found to be located within candidate genes,
allowing the researchers to use the candidate gene
approach on a genome-wide scale. SNPs have some
drawbacks but when compared to other markers they
are more efficient and SNP consortium is growing to
meet the requirements of genome-wide scans. Genomic
selection should be able to at least double the rate
of genetic gain in the dairy industry but the
incorporation of genomic information into the
breeding programs must be carefully considered. One
needs to have around 2000 genotypes means a large
reference population (population with both phenotype
and genotype recorded) to achieve meaningful
increases in accuracy. The available information,
selection objectives, production circumstances and
benefit/cost analysis must be evaluated in order to
decide whether or not the population is suitable for
GS implementation, and which would be the most
convenient way, if any, for its implementation.
Animal breeders will need to lead the way on the
integration of genomic and phenotypic data into a
new era of genome-enabled animal improvement and
management.
Keywords: Breeding practice,
Domestic Animals, DNA, Genome
