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                            Original Research
                            
                            
                            4.
                            Antibiotic resistance profile of Escherichia coli
                            isolates from Colibacillosis in and around Pantnagar, 
                            India -
                            
                            
                            Sumit Joshi, Rashmi Singh, S. P. Singh
                            Vet World. 2012; 5(7): 405-408
              
               
              
              doi: 
              10.5455/vetworld.2012.405-408
              
              
               
              
              
              
   
 
              
               
               
               
              
              
              Abstract
              
              
                            
                            Aim: 
                            The present study was designed to study antibiotic 
                            resistance profile of E. coli isolates from 
                            colibacillosis in layers in and around Pantnagar. 
              
                            
                             
                            Materials and Methods: A total of 20 isolates of
                            E. coli were recovered from 35 cases of 
                            colibacillosis in layers during necropsy. 
                            Antibiogram was studied via disc diffusion method 
                            against 12 antibiotics. 
              
                            
                             Results: Results 
                            showed multiple drug resistance in 52.63% E. coli
                            isolates. Serotyping of these isolates revealed 
                            10 'O' group serotypes, predominantly O80 and O84 
                            accounting for 31.57%. O80, O110, O119 and O132 have 
                            previously been isolated from human suggesting its 
                            zoonotic importance. A high degree of resistance was 
                            seen against cephalexin (73.68%) whereas 
                            chloramphenicol was found to be maximally (100%) 
                            effective. Emergence of enhanced mechanism of 
                            resistance to a variety of frequently used 
                            antibiotics is an increasing public health problem. 
              
                            
                            
                            Conclusion: It can be concluded that animals 
                            and human are at potential risk of acquiring 
                            infection with multi drug resistant strain of E. 
                            coli.
                            Keywords: 
                            Antibiotic sensitivity, E. coli, Layers, 
                            Serotypes