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Original Research
2.
Clinical changes in sodium monoiodoacetate–induced
stifle osteoarthritis model in dogs -
N V Goranov
Vet World. 2012; 5(3): 138-144
doi:
10.5455/vetworld.201
2.138-144
Abstract
In six dogs, experimental model of osteoarthritis
(OA) was reproduced by intraarticular injection of
sodium monoiodoacetate (MIA) in left stifle
joints. Contralateral joints served as control.
The clinical status and some goniometric
parameters were monitored before MIA introduction
and at post injection days 30, 60 and 105. The
results showed convincingly that the used
experimental chemical OA model reproduced
successfully the disease in canine stifle joints.
The studied clinical indices correlated with the
severity of disease.
Кeywords: dogs, stifle
joint, sodium monoiodoacetate, osteoarthritis
