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              Open Access  
Copyright: The authors. This article is an open access 
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(http://creativecommons.org/licenses/by/2.0) which permits unrestricted use, 
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              Research (Published 
online :  05-10-2013) 
8. Hemato-biochemical and therapeutic studies on 
Escherichia coli associated with concurrent enteric infection in lambs - 
Nuzhat Hassan, G. N. Sheikh, H. U. Malik, M. Shaheen and M. M. WillayatVeterinary World, 6(11): 870-873
 
                
              doi: 
              10.14202/vetworld.2013.870-873 
                
              
              
          
 
              Abstract 
 
              Aim: The trials were designed 
              on 30 lambs of age below 2 weeks exhibiting the symptoms of 
              colibacillosis.Materials and Methods: Isolation of organism and 
              identification of pathogenic Escherichia coli was confirmed by 
              standard cultural, microbiological, serological, and biochemical 
              tests. Venous blood was collected aseptically for hematological 
              studies.
 Result: Bacteriological examinations of fecal sample were 
              positive for E.coli and isolates identified on the basis of 
              morphological, cultural, and biochemical characteristics provided 
              further confirmation. Hematological indices recorded significant 
              (p > 0.05) increase in the packed cell volume, total leucocyte 
              count, lymphocyte, and neutrophil percentage, whereas biochemical 
              indices recorded significant decrease in the serum glucose, 
              protein and serum albumin/ globulin levels. Treatment regimen in 
              four different groups, suggested, gentamicin and ciprofloxacin 
              effective drugs followed by neomycin and co-trimoxazole.
 Conclusion: Study suggested significant (P > 0.05) 
              alteration in hemato-biochemical parameters whereas results 
              indicated gentamicin and ciprofloxacin as most effective drugs.
 Keywords: enteric infection, Escherichia coli, hemato-biochemical, 
              lambs
 
 
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