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R esearch
(Published online:
21-11-2015)
6.
Therapeutic management of botulism in
dairy cattle -
S. Jegaveera Pandian, M. Subramanian, G. Vijayakumar, G. A.
Balasubramaniam and K. Sukumar
Veterinary World, 8(11): 1305-1309
doi:
10.14202/vetworld.2015.1305-1309
S. Jegaveera Pandian:
Division of Livestock and Fisheries Management, ICAR Research
Complex for Eastern Region, Patna, Bihar, India;
jeganicar@gmail.com
M. Subramanian:
Department of Veterinary Clinical Medicine, Veterinary College
and Research Institute, Namakkal- 637 002, Tamil Nadu, India;
subramanianvet1955@gmail.com
G. Vijayakumar:
Department of Veterinary Clinical Medicine, Veterinary College
and Research Institute, Namakkal- 637 002, Tamil Nadu, India;
drvijaymvc@gmail.com
G. A. Balasubramaniam:
Department of Veterinary Pathology, Veterinary College and
Research Institute, Namakkal- 637 002, Tamil Nadu, India;
gabalasubramaniam@gmail.com
K. Sukumar:
Department of Veterinary Public Health and Epidemiology,
Veterinary College and Research Institute, Tirunelveli- 627 001,
Tamil Nadu, India;
drksugu@gmail.com
Received: 08-06-2015, Revised: 26-10-2015, Accepted: 05-10-2015,
Published online: 21-11-2015
Corresponding author:
S. Jegaveera Pandian, e-mail: jeganicar@gmail.com
Citation:
Pandian SJ, Subramanian M, Vijayakumar G, Balasubramaniam GA,
Sukumar K (2015) Therapeutic management of botulism in dairy
cattle,
Veterinary World 8(11):
1305-1309.
Abstract
Aim:
To report the successful recovery of few dairy cattle from
botulism in response to a modified therapeutic strategy.
Materials and Methods:
Seventy four naturally-occurring clinical cases of bovine
botulism encountered during the period of 2012-2014 which were
confirmed by mouse lethality test became material for this
study. Affected animals were made into three groups based on the
treatment modifications made during the course of study.
Results and Discussion:
With the modified therapeutic regimen, 17 animals recovered
after 7-10 days of treatment. Clinical recovery took 2-30 days.
Animals which were not given intravenous fluid and calcium
recovered uneventfully. Cattle which were already treated with
intravenous fluids, calcium borogluconate, and antibiotics did
not recover. They were either died or slaughtered for salvage.
Conclusion:
In cattle with botulism, administration of Vitamin AD3E and
activated charcoal aid the clinical recovery. Besides, strictly
avoiding anti-clostridial antibiotics, fluid therapy, and
calcium therapy may facilitate the clinical recovery. Upon fluid
administration, the pulmonary congestion existed in the ailing
cattle might have worsened the anoxia. Administration of
antibiotics like penicillin, aminoglycosides, and tetracyclines
further worsen the neuronal paralysis by increasing the
availability of botulinum neurotoxin. Cattle in early botulism
have fair chances of recovery with the modified therapy.
Keywords:
botulism, cattle, neurotoxin, paralysis, therapy.
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