| 
              
              
              Open Access  
 
              
              
              
              Research 
              
              
(Published 
				online: 07-12-2016)  
              8. 
				
              Studies on alterations of clinical 
              and hemato-biochemical parameters before and after treatment in 
              calves naturally infected with theileriosis -
              
              
              J. P. Kachhawa, Surender Kumar, Ankita Sharma, A. P. Singh
              
              
              and Anil Ahuja 
              
              Veterinary World, 9(12): 1381-1385   
              
   
                
                
doi: 
              
				
				10.14202/vetworld.2016.1381-1385 
                
                J. P. Kachhawa:
                
              
                Department of 
                Clinical Veterinary Medicine, Ethics and Jurisprudence, College 
                of Veterinary & Animal Science, Rajasthan University of 
                Veterinary and Animal Sciences, Bikaner - 334 001, Rajasthan, 
                India; 
              
                jpkachhawa@gmail.com 
              Surender Kumar:
              
              
              Veterinary 
              Hospital, Haripura, Hanumangarh, Rajasthan, India; 
              
              cool.drsurender@rediffmail.com 
              Ankita Sharma:
              
              
              Department of 
              Clinical Veterinary Medicine, Ethics and Jurisprudence, College of 
              Veterinary & Animal Science, Rajasthan University of Veterinary 
              and Animal Sciences, Bikaner - 334 001, Rajasthan, India; 
              
              dr.ankitasharma.vet@gmail.com 
              A. P. Singh:
              
              
              Department of 
              Clinical Veterinary Medicine, Ethics and Jurisprudence, College of 
              Veterinary & Animal Science, Rajasthan University of Veterinary 
              and Animal Sciences, Bikaner - 334 001, Rajasthan, India; 
              
              drapsinghbikaner@yahoo.co.in 
              Anil Ahuja:
              
              
              Department of 
              Clinical Veterinary Medicine, Ethics and Jurisprudence, College of 
              Veterinary & Animal Science, Rajasthan University of Veterinary 
              and Animal Sciences, Bikaner - 334 001, Rajasthan, India; 
              anil_ahuja@mail.com   
              
              Received: 16-06-2016, Accepted: 05-11-2016, Published online: 
              07-12-2016   
				
              	
              	Corresponding author: 
              	
				J. P. Kachhawa, 
                e-mail: jpkachhawa@gmail.com 
 
              Citation: 
              
              Kachhawa JP, Kumar S, Sharma A, Singh AP, Ahuja A (2016) Studies 
              on alterations of clinical and hemato-biochemical parameters 
              before and after treatment in calves naturally infected with 
              theileriosis, Veterinary World, 9(12): 1381-1385. 
 
              
				Abstract 
 
              Aim: 
              The aim was to 
              determine hemato-biochemical alterations and to determine the 
              better treatment of theileriosis in naturally infected calves.
               
              Materials and 
              Methods: 
              A total of 74 
              Holstein crossbred calves below 6 months of age, of either sex 
              were included for present investigation in Bikaner. Based on the 
              clinical examinations and laboratory results, 20 calves included 
              for hemato-biochemical studies (before and after treatment) and 
              divided into two groups (having 10 calves each).  
              Results: 
              The clinical 
              examination of these calves revealed weakness, ticks infestations, 
              high fever above 104°F, pronounced swelling of prescapular, 
              prefemoral, parotid lymph nodes, loss of elasticity of skin, 
              anemia, lacrimal discharges, pulpy cornea, tachycardia, and 
              dyspnea. There was highly significant decrease (p<0.01) in 
              hemoglobin, total erythrocyte count, packed cell volume and total 
              leukocyte count, serum glucose, total protein, globulin and 
              albumin level and highly significant increase in aspartate 
              aminotransferase and alanine aminotransferase level as compared to 
              healthy control animals in Group I and II. The animals of Group II 
              treated with buparvaquone along with single blood transfusion 
              shows better recovery then animals of Group I treated with 
              bupavaqone and hematinic.  
              Conclusions:
              
              Significant changes were found in hemato-biochemical parameters in 
              theileria affected calves before treatment as compare to healthy 
              control calves. Significant improvement was observed in hemato-biochemical 
              parameters in buparvaquone and single blood transfusion treated 
              calves as compare to another group, so it is concluded that 
              buparvaquone and single blood transfusion is better combination 
              for treatment of theileriosis.  
              
              Keywords: 
              
              blood transfusion, buparvaquone, calves, hemato-biochemical, 
              theileriosis. 
 
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