Moringa oleifera leaf nanoemulsion attenuates polystyrene nanoplastic-induced hepatotoxicity and dysregulation of hepatic glucose metabolism in rats

Veterinary World Volume 19, Issue 10

Oct 2026

Citescore: 4.5
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ARTICLE

Moringa oleifera leaf nanoemulsion attenuates polystyrene nanoplastic-induced hepatotoxicity and dysregulation of hepatic glucose metabolism in rats

Putri Ayu Ika Setiyowati , Alfiah Hayati , Febriyansyah Saputra , Manikya Pramudya , Mochammad Aqilah Herdiansyah , Sasanaqia Maulidah , Mardhiah Hayati , Lina Afiifatul Abroroh , Anisatul Mufidah , A’liyatur Rosyidah , Shinta Cahyaning Dewi , Raden Joko Kuncoroningrat Susilo , Aunurohim Aunurohim , Vuanghao Lim
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¹ Doctoral Study Program in Mathematics and Natural Sciences, Faculty of Science and Technology, Universitas Airlangga, Kampus C, Mulyorejo, 60115, Surabaya, Indonesia.

² Department of Biology, Faculty of Science and Technology, Universitas Airlangga, Kampus C, Mulyorejo, 60115, Surabaya, Indonesia; Developmental Biology and Biomedical Science Research Group, Universitas Airlangga, Kampus C, Mulyorejo, 60115, Surabaya, Indonesia.

³ Department of Biology, Faculty of Science and Technology, Universitas Airlangga, Kampus C, Mulyorejo, 60115, Surabaya, Indonesia.

⁴ Department of Biology, Faculty of Science and Technology, Universitas Airlangga, Kampus C, Mulyorejo, 60115, Surabaya, Indonesia; Developmental Biology and Biomedical Science Research Group, Universitas Airlangga, Kampus C, Mulyorejo, 60115, Surabaya, Indonesia.

⁵ Doctoral Study Program in Mathematics and Natural Sciences, Faculty of Science and Technology, Universitas Airlangga, Kampus C, Mulyorejo, 60115, Surabaya, Indonesia.

⁶ Department of Biology, Faculty of Science and Technology, Universitas Airlangga, Kampus C, Mulyorejo, 60115, Surabaya, Indonesia.

⁷ Department of Biology, Faculty of Science and Technology, Universitas Airlangga, Kampus C, Mulyorejo, 60115, Surabaya, Indonesia.

⁸ Department of Biology, Faculty of Science and Technology, Universitas Airlangga, Kampus C, Mulyorejo, 60115, Surabaya, Indonesia.

⁹ Department of Biology, Faculty of Science and Technology, Universitas Airlangga, Kampus C, Mulyorejo, 60115, Surabaya, Indonesia.

¹⁰ Research Center for Vaccine and Drugs, National Research and Innovation Agency (BRIN), Jalan Raya Jakarta-Bogor KM 46, Cibinong 16911, Indonesia.

¹¹ Doctoral Study Program in Mathematics and Natural Sciences, Faculty of Science and Technology, Universitas Airlangga, Kampus C, Mulyorejo, 60115, Surabaya, Indonesia.

¹² Department of Engineering, Faculty of Advanced Technology and Multidiscipline, Universitas Airlangga, Kampus C, Mulyorejo, 60115, Surabaya, Indonesia.

¹³ Department of Biology, Faculty of Science and Data Analytics, Institut Teknologi Sepuluh Nopember, Surabaya 60111, Indonesia.

¹⁴ Nanodrug and Metabolomics Research Group, Pusat Kanser Tun Abdullah Ahmad Badawi, Universiti Sains Malaysia, Bertam 13200 Kepala Batas, Pulau Pinang, Malaysia.

Corresponding Author: Alfiah Hayati (alfiah-h@fst.unair.ac.id)

Setiyowati et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License.

https://doi.org/10.14202/vetworld.2026.4545-4568

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Veterinary World

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Moringa oleifera leaf nanoemulsion attenuates polystyrene nanoplastic-induced hepatotoxicity and dysregulation of hepatic glucose metabolism in rats

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