Hydrophilic nanosilica as a new larvicidal and molluscicidal agent for controlling of major infectious diseases in Egypt

Vet World Vol.10 September-2017 Article-6

Research Article

Veterinary World, 10(9): 1046-1051

https://doi.org/10.14202/vetworld.2017.1046-1051

Marwa M. Attia¹, Soliman M. Soliman², and Mahmoud A. Khalf³

1. Department of Parasitology, Cairo University, Giza, P.O. Box 12211, Egypt.
2. Department of Medicine and Infectious Diseases, Cairo University, Giza, P.O. Box 12211, Egypt.
3. Department of Veterinary Hygiene and Management, Faculty of Veterinary Medicine, Cairo University, Giza, P.O. Box 12211, Egypt.

Background and Aim: This research was conducted to evaluate the molluscicidal and mosquitocidal efficacy of silica nanoparticles in the eradication of the larvae and pupa of malaria and filariasis vector as well as vectors of rift-valley fever virus (Culex pipiens); Schistosoma mansoni vector (Biomphlaria alexandrina (snail and egg masses)).

Materials and Methods: Hydrophilic nanosilica particles (NSPs) were characterized using transmission electron microscope during the preliminary part of the study; the stages were exposed to upgrade concentrations of NSP from 50 to 1200 ppm each for 24-36 h exposure time. The highly effective concentrations were re-evaluated at lower exposure time as 3, 6, and 12 h.

Results: Lethal concentration (LC50) and LC90 versus mosquito larvae were (350 ppm/24 h and 1400 ppm/24 h, respectively). C. pipiens pupae proved slight high tolerance versus the effect of these nanoparticles as the two previous doses increased to 680 ppm/6 h and 1300 ppm/24 h. The LC50 and LC90 versus B. alexandrina were increased to 590 ppm/6 h and 980 ppm/48 h, respectively. Moreover, the embryonated snail egg masses appear more susceptible to the toxic effect of these nanoparticles than the non-embryonated eggs as the LC50 and LC90 were increased to 1450 ppm/12 h and 1250 ppm/48 h, respectively, for embryonated eggs, and it was 1400 ppm/24 h and 1890 ppm/48 h, respectively, for non-embryonated one.

Conclusion: The results open a new field for controlling the infectious diseases through eradication of their vectors by the way that avoids the resistance recorded from the successive chemical application in this field. Keywords: Biomphalaria alexandrina, Culex pipiens, Egypt, nanosilica, rift valley fever, schistosomiasis.

Keywords: Biomphalaria alexandrina, Culex pipiens, Egypt, nanosilica, rift valley fever, schistosomiasis.

How to cite this article: Attia MM, Soliman SM, Khalf MA (2017) Hydrophilic nanosilica as a new larvicidal and molluscicidal agent for controlling of major infectious diseases in Egypt, Veterinary World, 10(9): 1046-1051.

Received: 19-05-2017 Accepted: 10-08-2017 Published online: 11-09-2017

Corresponding author: Marwa M. Attia E-mail: marwaattia.vetpara@yahoo.com

DOI: 10.14202/vetworld.2017.1046-1051

Copyright: Attia, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.