Vet World Vol.11 February-2018 Article-20
Research Article
Veterinary World, 11(2): 215-220
https://doi.org/10.14202/vetworld.2018.215-220
Comparative ovicidal activity of Moringa oleifera leaf extracts on Fasciola gigantica eggs
2. Department of Parasitology and Animal Diseases, National Research Centre, Dokki, Giza, Egypt.
Background and Aim: The aim of the present study was comparing the ovicidal effect of different extracts as an alcoholic (Methanolic and Ethanolic) and aqueous Moringa oleifera leaf extracts on Fasciola gigantica non-embryonated and developed eggs.
Materials and Methods: Tested concentrations of extracts ranged from 12.5 to 800 mg/ml. Nitroxynil was used as reference drug with a dose of 100 mg/ml.
Results: M. oleifera alcoholic and aqueous extracts showed a concentration-dependent ovicidal effect on F. gigantica non-embryonated and developed eggs. Based on LC50 values, water extract showed the highest ovicidal activity since it registered the lowest values of 2.6 mg/ml on non-embryonated eggs. Non-embryonated eggs were more susceptible to aqueous extract than developed eggs. On the other hand, the developed eggs were more susceptible to ethanolic extract than non-embryonated eggs even the lowest LC50 (12.38 mg/ml).
Conclusion: M. oleifera leaf extracts especially aqueous extract could be a promising step in the field of controlling fascioliasis. Further, in vivo studies are needed to enlighten the therapeutic potential of M. oleifera extracts in treating F. gigantica infection. Keywords: Fasciola gigantica, leaf extract, Moringa oleifera, nitroxynil, ovicidal activity.
Keywords: Fasciola gigantica, leaf extract, Moringa oleifera, nitroxynil, ovicidal activity.
How to cite this article: Hegazi AG, Abdel Megeed KN, Hassan SE, Abdelaziz MM, Toaleb NI, El Shanawany EE, Aboelsoued D (2018) Comparative ovicidal activity of Moringa oleifera leaf extracts on Fasciola gigantica eggs, Veterinary World, 11(2): 215-220.
Received: 14-09-2017 Accepted: 10-01-2018 Published online: 19-02-2018
Corresponding author: Dina Aboelsoued E-mail: Dr.Dina.Aboelsoued@gmail.com
DOI: 10.14202/vetworld.2018.215-220
Copyright: Hegazi, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.