Vet World   Vol.14   April-2021  Article-32

First report of canine parvovirus molecular detection in Bangladesh

Background and Aim: Canine parvovirus (CPV) is the most important cause of mortality in dogs in many parts of the world. Clinical cases exhibit characteristic signs, including foul-smelling bloody diarrhea, vomiting, fever, and dehydration. This study assessed field and vaccine variants of parvovirus in the Chattogram metropolitan area, Bangladesh. The investigation also aimed to identify risk factors for this disease. This research is the first to identify the presence of CPV in Bangladesh through molecular examination.

Materials and Methods: From October to December 2019, a total of 100 dogs were included in the study. Rectal swabs were taken from all dogs. Twenty dogs showed clinical signs of parvovirus. All clinically affected animals along with 20 randomly selected healthy dogs were tested using amplification refractory mutation system (ARMS)-polymerase chain reaction (PCR) to identify variants from the samples. Logistic regression model analysis was performed to determine the possible risk factors for CPV.

Results: ARMS-PCR showed the presence of all three variants, CPV2a, CPV2b, and CPV2c, in clinically ill dogs, and vaccines available in the study area showed either CPV2a or CPV2b strain. The CPV2c variants showed a higher incidence than the other variants. All apparently healthy animals tested were molecularly negative. Multivariable logistic regression model (generalized linear mixed model) indicated that exotic breeds were 3.83 times more likely to be infected by CPV than local breeds. Furthermore, dogs reared in semi-intensive and extensive management systems were 3.64 and 3.79 times more likely to be infected, respectively, than those reared in an intensive management system.

Conclusion: These findings provide practitioners and pet owners information on the occurrence of different variants and help design effective prevention strategies for CPV infection. Keywords: Bangladesh, canine parvovirus, CPV2a, CPV2b, CPV2c.

Keywords: Bangladesh, canine parvovirus, CPV2a, CPV2b, CPV2c.

How to cite this article: Hasib FMY, Akter S, Chowdhury S (2021) First report of canine parvovirus molecular detection in Bangladesh, Veterinary World, 14(4): 1038-1043.

Received: 07-10-2020  Accepted: 15-03-2021     Published online: 29-04-2021

Corresponding author: Sharmin Akter   E-mail: sharmin_rhima@yahoo.com

DOI: 10.14202/vetworld.2021.1038-1043

Copyright: Hasib FMY, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.