Research Article | 15 Feb 2022

Effects of urea supplementation on ruminal fermentation characteristics, nutrient intake, digestibility, and performance in sheep: A meta-analysis

Teguh Wahyono1,2, Mohammad Miftakhus Sholikin1,2, Yusuf Konca3, Taketo Obitsu4, Sadarman Sadarman2,5, and Anuraga Jayanegara2,6Show more
VETERINARY WORLD | pg no. 331-340 | Vol. 15, Issue 2 | DOI: 10.14202/vetworld.2022.331-340
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Abstract

          
Background and Aim: As a non-protein nitrogen source, urea is a popular, low cost, and easily obtained protein supplement. The objective of the present study was to perform a meta-analysis of the effects of urea supplementation on rumen fermentation and sheep performance.
Materials and Methods: A total of 32 experiments from 21 articles were compiled into a dataset. The levels of dietary urea varied from 0 to 31 g/kg of dry matter (DM). Parameters observed were rumen fermentation product, nutrient intake, nutrient digestibility, and sheep performance. This dataset was analyzed using a mixed model methodology, with urea supplementation levels as fixed effects and the different experiments as random effects.
Results: Increasing levels of urea were associated with increases (p=0.008) in rumen pH, butyrate (C4) production, and ammonia (NH3–N) concentration. Urea supplementation had minor effects on total volatile fatty acids (p=0.242), total protozoa (p=0.429), and the microbial N supply (p=0.619), but tended to increase methane production (CH4; p<0.001). Supplementation of urea increased the intake of dry matter (DM; p=0.004) and crude protein (CP; p=0.001). Digestibility parameters, such as DM digestibility (DMD) and CP digestibility (CPD), also increased (p<0.01) as a result of urea supplementation. Retained N (p=0.042) and N intake (p<0.001) were higher with increasing levels of urea supplementation. In terms of animal performance, supplementation of urea increased average daily gain (ADG; p=0.024), but decreased the hot carcass weight percentage (p=0.017).
Conclusion: This meta-analysis reports the positive effects of urea supplementation on rumen fermentation products (i.e., pH, C4, and NH3–N), intake (DM, CP, and N), digestibility (DMD and CPD), and ADG in sheep. Keywords: meta-analysis, sheep, supplementation, urea.
          
Keywords: meta-analysis, sheep, supplementation, urea.