Vet World Vol.15 May-2022 Article-9
Research Article
Veterinary World, 15(5): 1215-1220
https://doi.org/10.14202/vetworld.2022.1215-1220
Antibiotic resistance and associated resistance determinants in different Salmonella enterica serovars isolated from pigs in Argentina
2. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina.
3. Servicio Antimicrobianos, National and Regional Reference Laboratory in Antimicrobial Resistance, Instituto Nacional de Enfermedades Infecciosas (INEI)-ANLIS "Dr. C. Malbran," Buenos Aires, Argentina.
4. Antimicrobial Resistance Special Program, Communicable Diseases and Environmental Determinants of Health, Pan American Health Organization, Washington, DC, United States of America.
Background and Aim: Salmonellosis is one of the most common foodborne diseases in the world, and the increasing antibiotic resistance in Salmonella enterica subsp. enterica recovered from food animals constitutes an important risk from a One Health approach. This study aimed to characterize antibiotic resistance and some of its associated resistance determinants in different S. enterica serovars isolated from pigs in Argentina.
Materials and Methods: A retrospective study was conducted on Salmonella strains isolated between 2011 and 2015 from pigs in the Pampean region of Argentina. The antimicrobial susceptibility patterns to 21 antimicrobials and some antibiotic resistance determinants were characterized in 55 Salmonella isolates, representing 58 farms.
Results: We identified 56% (n=30) of the strains as multidrug-resistant, where resistance to tetracycline (62%, n=34), ampicillin (53%, n=29), nalidixic acid (53%, n=29), chloramphenicol (33%, n=18), and trimethoprim-sulfamethoxazole (31%, n=17) was most common. The wide range of resistance to ampicillin correlates with the presence of TEM type β-lactamases in the strains. However, high susceptibility was found in the new generation of β-lactams. Fluoroquinolone resistance is a major concern. Most strains with decreased susceptibility to ciprofloxacin showed gyrA mutations and plasmid-mediated quinolone resistance gene qnrB.
Conclusion: Here, we identified broad resistance to some antibiotics frequently used in human therapeutics and several easily transferable resistance mechanisms that could endanger public health. Keywords: environment, health, livestock, salmonellosis.
Keywords: environment, health, livestock, salmonellosis.
How to cite this article: Parada J, Galas M, Faccone D, Tamiozzo P, Carranza A (2022) Antibiotic resistance and associated resistance determinants in different Salmonella enterica serovars isolated from pigs in Argentina, Veterinary World, 15(5): 1215-1220.
Received: 01-10-2021 Accepted: 16-03-2022 Published online: 20-05-2022
Corresponding author: Julián Parada E-mail: jparada@ayv.unrc.edu.ar
DOI: 10.14202/vetworld.2022.1215-1220
Copyright: Parada, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.