Research Article | 15 Feb 2024

Influence of idiopathic epilepsy on blood pressure and electrocardiography in dogs treated with phenobarbital

Yolanda Paim Arruda Trevisan1, Maria Sabrina de Freitas2, Maria Natalia de Freitas3, Jaqueline Konrad4, Juliano Bortolini5, Ana Carolina Schipiura6, Ana Flávia Borges de Freitas7, Sarah Szimanski Pazzini8, Arleana do Bom Parto Ferreira de Almeida9, and Valéria Régia Franco Sousa10Show more
VETERINARY WORLD | pg no. 356-360 | Vol. 17, Issue 2 | DOI: 10.14202/vetworld.2024.356-360
Citations:

Cite this Article

  • APA
  • MLA
  • Chicago
  • Vancouver
  • Harvard

              
            

Abstract

Background and Aim: Dogs with idiopathic epilepsy (IE) experience a shortened lifespan, neurobehavioral changes, and an increased risk of comorbidities during the interictal period. There have been several reports of sudden death in humans with epilepsy, suggesting changes in cardiac rhythm secondary to seizures. In veterinary medicine, there are still no such conclusive studies. The present study aimed to evaluate blood pressure values, electrocardiographic findings, and laboratory parameters in dogs with IE treated with phenobarbital and to correlate these findings with possible cardiac alterations.

Materials and Methods: Twenty-one dogs were divided into 11 healthy dogs and 10 idiopathic epileptic dogs for blood analysis, computerized electrocardiogram, and oscillometer-based blood pressure measurement.

Results: QRS complex and S-T interval values differed significantly between groups, but blood pressure values were not significantly different.

Conclusion: IE can occur with alterations in cardiac conduction and is a pathological condition. Keywords: arterial hypertension, cardiac conduction, electrocardiogram, epileptic seizures, hemogasometry, tachycardia.

Keywords: arterial hypertension, cardiac conduction, electrocardiogram, epileptic seizures, hemogasometry, tachycardia.