Vet World   Vol.17   June-2024  Article - 15 

Research Article

Veterinary World, 17(6): 1307-1310

https://doi.org/10.14202/vetworld.2024.1307-1310

Comparison of SensPERT® Leishmania rapid test with two other immunochromatographic tests for the diagnosis of canine visceral leishmaniasis in Brazil

Mariana Elisa Pereira1, Maria Clara Bianchini Neves2, Arleana do Bom Parto Ferreira de Almeida3, and Valéria Régia Franco Sousa3
1. Postgraduate Program in Veterinary Science, Faculty of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá, Mato Grosso, Brazil.
2. Graduate Program in Veterinary Medicine, College of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá, Mato Grosso, Brazil.
3. Faculty of Veterinary Medicine, Federal University of Mato Grosso, Cuiabá, Mato Grosso, Brazil. 

Background and Aim: In urban environments, dogs serve as the primary reservoir for visceral leishmaniasis (VL). Rapidly diagnosing canine VL through tests enables early treatment and a favorable prognosis. This study aimed to assess the diagnostic performance of the SensPERT® Leishmania test kit (Dechra®), Alere® Leishmaniasis Ac test kit, and the rapid test dual path platform (TR-DPP®) Bio-Manguinhos in detecting VL. 

Materials and Methods: 30 serum samples from reactive VL dogs and 30 serum samples from healthy dogs were employed for assessing the sensitivity and specificity variation between SensPERT® Leishmania test kit, Alere® Leishmaniasis Ac test kit, and rapid test dual platform – TR-DPP®. 

Results: The SensPERT® Leishmania test outperformed Alere® and TR-DPP® in terms of sensitivity, specificity, positive and negative predictive values and demonstrated near-perfect concordance with Alere® and substantial concurrence with TR-DPP®. 

Conclusion: The SensPERT® Leishmania rapid test proved to be a promising test in the detection of VL in dogs. 

Keywords: immunochromatography, Leishmania infantum, reservoir.


How to cite this article: Pereira ME, Neves MCB, Almeida ABPF, and Sousa VRF (2024) Comparison of SensPERT® Leishmania rapid test with two other immunochromatographic tests for the diagnosis of canine visceral leishmaniasis in Brazil, Veterinary World, 17(6): 1307–1310.

Received: 2024-02-22    Accepted: 2024-05-28    Published online: 2024-06-19

Corresponding author: Valéria Régia Franco Sousa    E-mail: valeriaregia27@gmail.com

DOI: 10.14202/vetworld.2024.1307-1310

Copyright: Pereira, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/ by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/ publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.