Vet World Vol.17 June-2024 Article - 26
Research Article
Veterinary World, 17(6): 1397-1404
https://doi.org/10.14202/vetworld.2024.1397-1404
Serum insulin-like growth factor-1 and leptin concentrations in Black Bengal goats at different ages and gestation periods and their relationship to kid growth performance
2. Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, 10330, Thailand.
3. Multi-Omics for Functional Products in Food, Cosmetics and Animals Research Unit, Chulalongkorn University, Bangkok, 10330, Thailand.
Background and Aim: The impact of maternal hormone concentration on kid growth performance in relation to insulin-like growth factor 1 (IGF-1) and leptin is minimal. This study examined IGF-1 and leptin levels at varying ages and gestation periods for their correlation with Black Bengal goat kids’ growth during the preweaning phase.
Materials and Methods: Blood samples were collected from 43 dams with different reproductive cycles and 28 prepubertal goats to measure serum concentrations of IGF-1 and leptin. Among dams, both hormones were investigated in different age ranges (<2, 2–3, 3–4, and >4 years old) and reproductive cycles (non-pregnancy, early gestation (1–50 days), mid-gestation (51–100 days), late gestation (101–135 days), and the last 15 days before delivery). After delivery, 65 kids from 34 dams were weighted weekly for 8 weeks to calculate average daily weight gain (ADG) at 0–4 weeks (ADG0–4 W) and 4–8 weeks (ADG4–8 W) and growth performance, including weight (W), height (H), length (L), chest girth (C) measured at birth (W0, H0, L0, and C0) and at 10 weeks of age (W10, H10, L10, and C10) were related to hormone serum concentrations in their dams at different gestation periods including the last 15 days before delivery.
Results: Dams had higher mean serum IGF-1 (p < 0.001) and leptin (p < 0.05) than prepubertal goats. Dams at late gestation had higher IGF-1 concentrations than those at early and mid-gestation and during the last 15 days before delivery. However, it was consistent with non-pregnant goats. The kid’s growth performance correlated positively with IGF-1 concentration, which was collected in the last 15 days before delivery. Multivariate analysis showed that ADG0–4 W was higher in kids born from dams with high IGF-1 than those with low IGF-1 measured during the last 15 days of delivery, whereas leptin tended to have a similar effect.
Conclusion: Serum IGF-1 and leptin concentrations of dams measured during the last 15 days before delivery were associated with kid’s growth during the preweaning period.
Keywords: Black Bengal goat, growth performance, insulin-like growth factor 1, leptin.
How to cite this article: Buranakarl C, Chamsuwan S, and Nuntapaitoon M (2024) Serum insulin-like growth factor-1 and leptin concentrations in Black Bengal goats at different ages and gestation periods and their relationship to kid growth performance, Veterinary World, 17(6): 1397–1404.
Received: 2024-02-20 Accepted: 2024-05-30 Published online: 2024-06-28
Corresponding author: E-mail:
DOI: 10.14202/vetworld.2024.1397-1404
Copyright: Buranakarl, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/ by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/ publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
