Vet World Vol.17 June-2024 Article - 7
Research Article
Veterinary World, 17(6): 1238-1250
https://doi.org/10.14202/vetworld.2024.1238-1250
Effect of different synbiotic administration methods on growth, carcass characteristics, ileum histomorphometry, and blood biochemistry of Cobb-500 broilers
2. Department of Theriogenology, Agriculture and Forestry University, Faculty of Animal Science, Veterinary Science and Fisheries, Rampur Chitwan, 00977 Nepal.
3. Department of Veterinary Microbiology, Agriculture and Forestry University, Faculty of Animal Science, Veterinary Science and Fisheries, Rampur Chitwan, 00977 Nepal.
4. Department of Animal Nutrition and Fodder Production, Faculty of Animal Science, Veterinary Science and Fisheries, Rampur, Chitwan, Nepal.
Background and Aim: To combat enteric infections and antibiotic resistance in the poultry industry, researchers seek alternatives such as probiotics, prebiotics, and synbiotics as growth promoters. Synbiotics support probiotic growth through the supply of essential nutrients. The study’s objectives were to assess the most effective delivery methods for synbiotics and evaluate their growth, histomorphometric, and hematological impacts on Cobb-500 broilers.
Materials and Methods: Two studies, independently conducted, employed a completely randomized design. One hundred and eighty viable eggs in the first trial were assigned to three groups: Control (T1), sterile water (T2), and synbiotic in sterile water (T3). On the 21st day of hatching, hatchability, day-old body weights, and ileum samples for histomorphometric analysis were recorded. In the second trial, out of 500 viable eggs, 200 eggs were fed in ovo with synbiotics (PoultryStar® sol, Biomin Singapore Pte Ltd, Singapore) on 17.5 days and 300 were set aside without in ovo injection. The treatments were control (T1), in water synbiotic (T2), in ovo synbiotic (T3), combination of in ovo synbiotic and synbiotic in feed (T4), and synbiotic in feed only (T5). On 21 and 42 days, blood, ileum, and visceral organ samples were collected for laboratory analysis. Data on weight gain, daily feed intake, and water consumption were recorded for 42 days.
Results: The initial experiment’s results revealed a decrease in hatchability, slight weight increase, and significant intestinal morphological changes with the use of an in ovo synbiotic. Applying synbiotic through various methods in the second trial yielded better growth results, lower blood cholesterol, and significantly longer (p < 0.05) villi on 21 days.
Conclusion: Using the in ovo method to administer synbiotics lowered hatchability. Use of synbiotics with any method or in combination enhances growth, ileum structure, dressing yield, feed efficiency, and cholesterol levels in blood. Synbiotics enhance gut health and overall performance in broilers when used through diverse approaches.
Keywords: growth performance, gut health, histomorphometry, in ovo, synbiotic.
How to cite this article: Acharya A, Devkota B, Basnet HB, and Barsila SR (2024) Effect of different synbiotic administration methods on growth, carcass characteristics, ileum histomorphometry, and blood biochemistry of Cobb-500 broilers, Veterinary World, 17(6): 1238–1250.
Received: 2024-02-13 Accepted: 2024-05-15 Published online: 2024-06-08
Corresponding author: E-mail:
DOI: 10.14202/vetworld.2024.1238-1250
Copyright: Acharya, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/ by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/ publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
