Vet World Vol.17 May-2024 Article - 22
Research Article
Veterinary World, 17(5): 1130-1138
https://doi.org/10.14202/vetworld.2024.1130-1138
Changes in blood biochemical parameters in highly productive cows with ketosis
2. Department of Veterinary and Sanitary Expertise of Livestock Product and Hygiene of Farm Animals, Faculty of Veterinary Medicine, P.A. Stolypin Omsk State Agrarian University, Omsk, Russian Federation.
3. Department of Agronomy and Forestry, Agrotechnological Faculty, Manash Kozybaev North Kazakhstan University, Petropavlovsk, Kazakhstan.
4. Department of Agriculture and Bioresources, Faculty of Veterinary Medicine and Agricultural Management, Shakarim University of Semey, Semey, Kazakhstan.
5. Department of Livestock, North Kazakhstan Research Institute of Agriculture, Beskol, Kazakhstan.
Background and Aim: Biochemical blood testing is the main diagnostic indicator of the clinical condition of highly productive animals and a method of determining changes in metabolic disorders. This study focuses on metabolic changes (ketosis), which are of the utmost importance in the assessment of the health status of animals, as well as differences in intergroup characteristics. The main focus of this study is to demonstrate the influence of subclinical ketosis in highly productive cows on changes in biochemical blood parameters during different physiological periods to further prevent this disease, adjust feeding rations, and prevent premature culling of animals. This study aimed to evaluate and establish changes in the biochemical status dynamics of highly productive cows with metabolic disorders in an industrial livestock complex.
Materials and Methods: Blood samples were systematically collected from highly productive cows of the Simmental breed (n = 60) and served as the primary material for subsequent analyses. Each methodological step was designed to ensure evaluation of the metabolic changes associated with post-calving adjustments in highly productive dairy cows. This study employed a comprehensive approach integrating clinical assessments, laboratory analyses, biochemical evaluations, instrumental measurements, and statistical analyses.
Results: A biochemical blood test showed that the number of ketone bodies in the experimental group exceeded the norm, varied depending on the physiological state of the animals, and ranged from 0.89 to 1.45 mmol/L. At 10 days after calving, the highest indicator was 1.45 ± 0.05 mmol/L. This indicator was 1.05 mmol/L higher than that in the control group and exceeded the norm by 0.95.
Conclusion: Excess ketone bodies in the blood of animals led to accumulation in urine and milk, indicating a disturbance in metabolic processes in the body and a decrease in the quality of animal husbandry products. The sample size and the focus on a single breed from one geographical location may limit the generalizability of the findings. Further research should explore the mechanistic bases of ketosis development, potentially integrating genomic and proteomic approaches to understand the genetic predispositions and molecular pathways involved.
Keywords: biochemical composition of blood, ketone bodies, liver dystrophy, metabolism, phospholipids.
How to cite this article: Il Y, Il D, Zabolotnykh M, Savenkova I, Nurzhanova K, Zhantleuov D, Kozhebayev B, Akhmetova B, Satiyeva K, and Kurmangali L (2024) Changes in blood biochemical parameters in highly productive cows with ketosis, Veterinary World, 17(5): 1130–1138.
Received: 2023-10-21 Accepted: 2024-04-26 Published online: 2024-05-17
Corresponding author: E-mail:
DOI: 10.14202/vetworld.2024.1130-1138
Copyright: Yelena, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/ by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/ publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
