Changes in the metabolomic profiles of mammary secretion in relation to dam litter size and parity number in Black Bengal goats

Vet World Vol.17 July-2024 Article - 6

Research Article

Veterinary World, 17(7): 1469-1481

https://doi.org/10.14202/vetworld.2024.1469-1481

Tien Thi Phuong Vo¹, Chollada Buranakarl¹, Sumonwan Chamsuwan¹, Sumpun Thammacharoen¹, Panupat Ratchakom², Morakot Nuntapaitoon^3,4, and Sarn Settachaimongkon⁵

1. Department of Physiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
2. Department of Livestock Development, Chiang Rai Provincial Livestock Office, Chiang Rai, Thailand.
3. Department of Obstetrics, Gynaecology and Reproduction, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.
4. Multi-Omics for Functional Products in Food, Cosmetics and Animals Research Unit, Chulalongkorn University, Bangkok, Thailand.
5. Department of Food Technology, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.

Background and Aim: The colostrum is essential for a kid’s survival and development. The metabolomic profiles of mammary secretion in goats are limited. This study investigated the metabolomic profiles of mammary secretion in purebred Black Bengal goats and their relationships with litter size and parity number.

Materials and Methods: 500 MHz nuclear magnetic resonance was used to analyze the metabolomic profiles of 43 colostrum and milk samples collected on delivery day and day 7 after parturition, respectively.

Results: Fifty-one metabolites were distinguished between colostrum and milk based on heatmap visualization and hierarchical cluster analysis. In colostrum, most compounds were present in significantly greater amounts than in milk. Milk of goats with multiple litter sizes had higher levels of lactose while fat, protein, total solids, solid not fat, and most of the metabolites were lower. The parity number of dams shows no difference in the composition of all components between primiparous and multiparous goats.

Conclusion: The components in colostrum were significantly more concentrated than those in milk. The multiple litter sizes in dams led to a significant impact on the composition of lactose and other milk metabolites.

Keywords: black Bengal goats, colostrum, litter size, metabolite, milk, parity number.

How to cite this article: Vo TTP, Buranakarl C, Chamsuwan S, Thammacharoen S, Ratchakom P, Nuntapaitoon M, and Settachaimongkon S (2024) Changes in the metabolomic profiles of mammary secretion in relation to dam litter size and parity number in Black Bengal goats, Veterinary World, 17(7): 1469–1481.

Received: 2024-03-13 Accepted: 2024-06-11 Published online: 2024-07-07

Corresponding author: Chollada Buranakarl E-mail: bchollad@chula.ac.th

DOI: 10.14202/vetworld.2024.1469-1481

Copyright: Vo, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/ by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/ publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.