Vet World Vol.17 March Article - 21
Research Article
Veterinary World, 17(3): 690-699
https://doi.org/10.14202/vetworld.2024.690-699
Antimicrobial resistance profiles of Escherichia coli derived from an integrated agroforestry-livestock system in Deli Serdang Regency, Indonesia
1 Department of Animal Husbandry, Faculty of Science and Technology, Universitas Tjut Nyak Dhien, Medan, Indonesia.
2 Department of Forestry, Faculty of Forestry, Universitas Sumatera Utara, Medan, Indonesia.
3 Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, University of Maiduguri, Maiduguri, Borno State, Nigeria.
4 Department of Pharmacy, Faculty of Pharmacy, Universitas Tjut Nyak Dhien, Medan, Indonesia.
Background and Aim: Antimicrobial resistance (AMR) has become a significant global concern. Epidemiological data do not provide a robust description of the potential risks associated with AMR in the integrated agroforestry-livestock systems in Indonesia. Thus, the present study investigated the phenotypic and multidrug resistance (MDR) profiles of Escherichia coli strains isolated from the feces of livestock raised in the agro-silvopastoral system in Deli Serdang Regency, North Sumatra Province.
Materials and Methods: A standard microbiological culture procedure was followed to isolate the organism and test antibiotic susceptibility using the Kirby-Bauer disk diffusion protocol. Furthermore, the multiple antibiotic resistance index was determined. Univariate analysis was conducted to identify the risk factors associated with AMR.
Results: The vast majority (77.5%) of livestock farmers were aged >30 years. All farmers were men and had no higher education (100% of them). The majority of the animal species managed were cattle and goats (37.5% each) and the livestock grazing pasture system (67.5%). In addition, the majority of farmers reported high antimicrobial use on their farms (87.5%). Of the samples (n = 142) analyzed, n = 70 were positive, with an overall prevalence of 44.4%. The species-specific prevalences of E. coli were 32.5%, 47.8%, and 50% in buffalo, goat, and cattle, respectively. Ampicillin and tetracyclines exhibited high resistance levels among the studied animal species. A relatively lower MDR for E. coli was associated with grazing on the pasture.
Conclusion: The findings from the current study provide baseline epidemiological information for future robust studies aimed at elucidating the drivers and patterns of AMR in agro-silvopastoral systems in the study area or elsewhere.
Keywords: agro-silvopastoral, antimicrobial Resistance, Escherichia coli,Indonesia, livestock, multidrug resistance.
How to cite this article: Dewi RR, Nuryawan A, Jajere SM, Sihombing JM, and Tambunan IJ (2024) Antimicrobial resistance profiles of Escherichia coli derived from an integrated agroforestry-livestock system in Deli Serdang Regency, Indonesia, Veterinary World, 17(3): 690-699.
Received: 11-11-2023 Accepted: 05-03-2024 Published online: 22-03-2024
Corresponding author: E-mail:
DOI: 10.14202/vetworld.2024.690-699
Copyright: Dewi, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/ by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/ publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
