Vet World   Vol.17   October-2024  Article - 7 

Review Article

Veterinary World, 17(10): 2253-2258

https://doi.org/10.14202/vetworld.2024.2253-2258

Low-dose radiation research insights in experimental animals: A gateway to therapeutic implications

Nayanatara Arunkumar1, Megha Gokul1, Harini Narayanam2, and A. K. Ananya3
1. Department of Physiology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Karnataka, Manipal, 576104, India.
2. Department of Physiology, Manipal University College Malaysia, Melaka, Malacca, Malaysia.
3. Srinivas Institute of Medical Sciences and Research Center, Mangaluru, Karnataka, India. 

In recent years, a significant research effort has been underway to explore the effects of low-dose radiation (LDR). Animal models play a key role in various fields of research, including biomedicine, pharmaceutical, environmental, and behavioral studies. The use of animal models has been an invaluable tool in radiation research for understanding radiation biology, assessing radiation risks, and developing strategies for radiation protection and medical management. In the present review, the initial part focuses on the deleterious effects of high-dose radiation, and in correlation to that, in the later part of the review, the emphasis has been given to experimental approaches to explore the beneficial effects of LDR using animal models. This review could help explore the innovative approach for future research targeting the therapeutic role of LDR in various diseases, including depression, Cancer, Parkinson’s disease, and Alzheimer’s disease. 

Keywords: animal model, high dose radiation, low dose radiation, mice, rat.


How to cite this article: Arunkumar N, Gokul M, Narayanam H, and Ananya AK (2024) Low-dose radiation research insights in experimental animals: A gateway to therapeutic implications, Veterinary World, 17(10): 2253-2258.

Received: 2024-06-25    Accepted: 2024-09-03    Published online: 2024-10-07

Corresponding author: Megha Gokul    E-mail: megha.gokul@manipal.edu

DOI: 10.14202/vetworld.2024.2253-2258

Copyright: Arunkumar, et al. This article is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/ by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http:// creativecommons.org/ publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.