Research Paper
Published on 2024-11-28
Exploring the therapeutic potential of Quercus ilex acorn extract in papillomavirus-induced lesions
Beatriz Medeiros-Fonseca, Ana I. Faustino-Rocha, Maria João Pires, Maria João Neuparth, Helena Vala, Cármen Vasconcelos-Nóbrega, Irene Gouvinhas, Ana Novo Barros, Maria Inês Dias, Lillian Barros, Margarida M. S. M. Bastos, Lio Gonçalves, Luís Félix, Carlos Venâncio, Rui Medeiros, Rui Miguel Gil da Costa, and Paula A. Oliveira
This study aimed to evaluate the in vivo safety and cancer chemopreventive activity of an infusion extract of Q. ilex in a transgenic mouse model of human PV (HPV)-16, which developed squamous cell carcinomas through a multistep process driven by HPV16 oncogenes.